All Things Saliva

Salimetrics is a valuable resource for learning more about saliva testing and related topics. We have many original writings on pertinent topics such as saliva, cortisol and saliva collection. As well, we have archives of academic papers, journal articles and abstracts we can provide for you or refer to you.

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Some Common Genetic Variants May Moderate the Stress Response through the HPA Axis: 07.05.09; One of the key responses to stress involves the activation of the hypothalamic-pituitary-adrenal (HPA) axis, which leads to the production of the steroid hormone cortisol in the adrenal cortex. Once released into the bloodstream, cortisol has widespread effects throughout the body, affecting metabolism, cell growth, the cardiovascular system, and the immune system. The net effect of these changes is to temporarily rebalance various systems in the body, minimizing some and maximizing others, in order to cope with the stress that is present…; PDF
Saliva Collection and Handling Advice (Protocols): 04.17.09; Researchers are increasingly turning to saliva testing because it allows samples to be collected in a convenient, non-invasive manner, and on a repeated basis. Anyone planning to use saliva testing must be aware, however, that it is important to follow proper collection and handling procedures in order to insure that the highest quality data is obtained. We offer the following advice based on our extensive experience with saliva collection and testing.; PDF
The cortisol awakening response, seasonality, stress and arousal: a study of trait and state influences.: April 2009; The aim of this study was to investigate the relationship between the cortisol awakening response (CAR) and two key state variables (morning stress and arousal) and the trait-like variable of seasonality as recent evidence suggests that the CAR is subject to both state and trait influences.
Salimetrics Spit Report - Fall 2008: November 2008; Welcome to the First Issue of The Spit Report
We hope that you find it to be useful and informative. Naturally, we would like you to look over the news from our company to see the new products and services that we are introducing as we grow. Equally important, however, we also want to offer information that will help you stay in touch with developments in saliva research and possibly help you in your own work. We would be happy if this newsletter begins to serve as an informal forum for saliva news, and we hope that researchers from outside our company will consider submitting brief reports that would be of general interest to our readers.
Entry of substances into saliva – effect of flow rate: 10.07.08; The non-invasive nature of saliva testing makes it the method of choice for many types of diagnostic and research applications. Before deciding to use saliva rather than some other body fluid, however, it is necessary to ask the following questions: first, how do the substances being measured get into saliva, and, secondly, what implications do the various pathways of entry have for the reliability of the measurements?; PDF
DHEA and DHEAS: An Introduction to Their Function and Measurement: 09.30.08; Dehydroepiandrosterone (DHEA) and its sulfated analog (DHEAS) are steroid hormones principally made in the adrenal cortex. DHEAS is the most abundant steroid in humans with serum concentrations 250-500 times higher than DHEA, 100-500 times higher than testosterone, and 1000-10000 times higher than estradiol.(1,2) DHEAS appears to serve primarily as a precursor molecule that is circulated to peripheral tissues throughout the body.; PDF
Salimetrics Assays: Applications and Research Ideas: PDF
Spit Basics (Saliva & the Mouth): 03.15.08; Learn about components of saliva and how they’re produced.
Immunoassay Basics: 03.01.08; Learn how immunoassays work through illustrations of some basic assay designs.
Saliva Collection Advice (Article): 03.01.08; Learn how collection techniques can affect your assay results.