Saliva Research News

Current Salivary Research News

*Note: Salimetrics provides this information for research use only (RUO). Information is not provided to promote off-label use of medical devices. Consult full text of article.

 

 
 

 

 
08.22.2014

Relationship between cortisol awakening response and other features of the diurnal cortisol rhythm

Author: Golden SH, et al. (2013) Psychoneuroendocrinology. Cumulative cortisol burden is known to influence neuropsychiatric and metabolic disorders. Up to 18 salivary cortisol samples were collected over 3 days from 935 White, Hispanic, and Black individuals…


08.04.2014

Researchers investigate the associations between hormones and friendship

Author: Kornienko O, et al (2014) Horm Behav. Hormones, Behavior, and Social Network Analysis: Exploring Associations Between Cortisol, Testosterone, and Network Structure. We used a new interdisciplinary paradigm of social network analysis (SNA)…


07.24.2014

ASU Researcher Shows How Stress Hormones Promote Brain’s Building of Negative Memories

Author: Segal S.K., et al. (2014) Neuroscience. Glucocorticoids interact with noradrenergic activation at encoding to enhance long-term memory for emotional material in women. Evidence from the animal literature suggests that post-training glucocorticoids…


07.18.2014

Blunted cardiovascular and cortisol reactivity to acute psychological stress

Author: De Rooij, SR (2013) International Journal of Psychophysiology. In a sample of 725 cohort members, an extensive psychological stress protocol was performed during which cardiovascular and cortisol responses were measured. In line with many previous studies, results…


07.07.2014

Greater fear reactivity and psychophysiological hyperactivity among infants with…

Author: Mills-Koonce WR, et al. (2014) J Child Psychol Psychiatry. The objective of this study was to examine group differences in fear reactivity and stress psychophysiology in infancy among children classified as having CP with CU (CP + CU), CP without CU (CP only),…


07.01.2014

Cortisol reactivity, delay discounting and percent body fat in Chinese urban young adolescents

Author: Lu Q, et al. (2014) Appetite. Anthropometry and body composition measurements were assessed in adolescents. The cortisol reactivity to Trier Social Stress Test for Children (TSST-C) and delay discounting were measured. The result showed…


06.20.2014

Salivary cortisol and behavior in a population of healthy dogs hospitalized for elective procedures

Author: Hekman JP, et al. (2012) Applied Animal Behaviour Science. The researchers assessed stress levels in two studies. Salivary cortisol samples and behavioral parameters were collected in healthy dogs hospitalized prior to elective procedures. A stress research tool…


06.12.2014

Behavioral reactivity to emotion challenge associated with cortisol reactivity and regulation

Author: Ursache, A, et al. (2013) Developmental Psychobiology This study examined relations of behavioral reactivity and regulation to emotional arousal in the context of fear and frustration to the cortisol response. They tested children at 7, 15, and 24 months…


06.04.2014

Measurements of Salivary Alpha Amylase and Salivary Cortisol in Hominoid Primates Reveal…

Author: Behringer, V, et al. (2013) PLoS ONE Salivary alpha amylase (sAA) is the most abundant enzyme in saliva. In this study, the researchers explored patterns of variation in sAA activity in bonobos and three other hominoid primates, chimpanzee,…


05.20.2014

Salimetrics SalivaLab Expands Salivary CLIA Testing Services for Clinical Research Organizations

Salimetrics SalivaLab Expands Salivary CLIA Testing Services for Clinical Research Organizations (CROs). CROs can benefit from out-sourcing saliva testing services to the Salimetrics SalivaLab or by using…


05.14.2014

Get Connected: First Annual Salivary BioScience Symposium

Steve W. Granger PhD, Salimetrics’ CSO attended the First Annual Salivary BioScience Symposium at Arizona State University and presented insights into immunoassay development to help biobehavioral…


05.07.2014

VIDEO: Spitting for Science - Research Matters

Spitting is a lot easier than giving a blood sample, but it can provide useful information about a person's hormone levels. Scientists know that people in close relationships, such as mothers and babies…


04.25.2014

Maternal sensitivity and infant and mother adrenocortical function across challenges

Author: Atkinson L, et al. (2013) Psychoneuroendocrinology. In this study, cortisol secretion of 297 infants and their mothers was assessed in response to different challenges at 16 and 17 months. Extensive, structured observations of maternal sensitivity were…


04.17.2014

Anxiety and chronic relationship stress moderate adrenocortical response in expectant parents

Author: Feinberg ME, et al. (2013) British Journal of Psychology. The study examines whether anxiety or chronic relationship stress alter the way that couple conflict affects cortisol levels for women and men during the transition to parenthood. Saliva samples, assayed…


04.08.2014

Pretreatment cortisol levels predict posttreatment outcomes among older adults /w depression in CBT

Author: Holland JM, et al. (2013) Psychiatry Research. The current study includes 54 older adults with depression who provided salivary cortisol samples at baseline and completed measures of depression at pretreatment and posttreatment, following a 12-week…


03.12.2014

Salivary alpha-Amylase and Cortisol Responsiveness Following Electrical Stimulation Stress

Author: Tamura A, et al. (2013) Pharmacopsychiatry This study focused on comparing the reactivity of 2 stress systems, the autonomic nervous system (ANS) and the hypothalamic-pituitary-adrenal (HPA) axis in patients with social anxiety disorder. Saliva…


02.28.2014

Early Childcare, Executive Functioning, and the Moderating Role of Early Stress Physiology

Author: Berry D, et al. (2013) Developmental Psychology. Intervention studies indicate that children's childcare experiences can be leveraged to support the development of executive functioning (EF). This study used data from a large population-based sample…


02.20.2014

Antepartum and postpartum saliva: normative values in women and correlations with serum

Author: Hampson, E, et al. (2013) Biology of Sex Differences Little normative information is available concerning expected concentrations of the major reproductive steroids in saliva during pregnancy and the extended postpartum. Matched serum and saliva specimens…


02.10.2014

Spouses’ Cortisol Associations and Moderators

Author: Papp, LM, et al. (2013) Family Process In this study, associations were examined between cortisol levels of wives and husbands in 47 heterosexual married couples. Both partners’ salivary cortisol levels were measured at the same moments seven…


01.28.2014

Poverty and Awakening Cortisol in Adolescence: The Importance of Timing in Early Life

Author: 01.28.14-awakening-cortisol-in-adolescence-the-importance-of-timing This study uses 15 years of prospective data from the Study of Early Child Care and Youth Development to assess how exposure to poverty during infancy, childhood, and adolescence is related to awakening…


01.24.2014

Sex-specific effects of mindfulness on romantic partners’ cortisol responses to conflict and…

Author: Laurent, H, et al. (2013) Psychoneuroendocrinology. The current study tested effects of dispositional mindfulness facets on young adult couples' cortisol responses to a conflict discussion stressor, as well as associations with psychological adjustment.…


01.15.2014

Dr. Granger to present Spit Camp workshop at Purdue University

Spit Camp at Purdue University The Department of Human Development and the College of Health and Human Sciences are pleased to announce a one-day salivary bioscience workshop at Purdue University. Dr.…


01.10.2014

Cognitive emotion regulation fails the stress test

Author: Raio, CM, et al. (2013) Proceedings of the National Academy of Sciences of the United States of America Cognitive emotion regulation has been widely shown in the laboratory to be an effective way to alter the nature of emotional responses. Because it is specifically under stressful conditions that we may…


12.31.2013

Cortisol awakening response in adolescents with acute sexual-abuse related PTSD

Author: Keshin, B. R, et al. (2013) Depression and Anxiety This pilot study utilized non-stressed home saliva collection three times a day for three days to assess the levels, diurnal variation and awakening response of cortisol in recently sexually abused adolescent…


12.27.2013

Salivary cytokines in adolescent girls: Intercorrelations, stability, and associations with serum

Author: Riis, JL, et al. (2013) Developmental Psychobiology In this study, cytokines in saliva and serum were analyzed across three annual assessments in healthy adolescent girls. Samples were assayed for GM-CSF, IFNγ, IL-1β, IL-2, IL-6, IL-8, IL-10, IL-12p70,…


12.11.2013

Maternal Disrupted Communication during Face-to-Face Interaction at 4 months

Author: Crockett, EE, et al. (2013) Infancy The study evaluated the association between maternal disrupted communication and the reactivity and regulation of the psychobiology of the stress response in infancy. Mothers and their 4-month-old infants…


12.11.2013

Maternal Disrupted Communication during Face-to-Face Interaction at 4 months

Author: Crockett, EE, et al. (2013) Infancy The study evaluated the association between maternal disrupted communication and the reactivity and regulation of the psychobiology of the stress response in infancy. Mothers and their 4-month-old infants…


12.04.2013

Anxiety and chronic relationship stress response to couple interaction in expectant parents

Author: Feinberg, M, et al. (2013) British Journal of Psychology The study examines whether anxiety or chronic relationship stress alter the way that couple conflict affects cortisol levels for women and men during the transition to parenthood. Saliva samples, assayed…


11.25.2013

Cumulative effects of early poverty on cortisol in young children

Author: Blair, C, et al. (2013) Psychoneuroendocrinology The relation of the cumulative experience of poverty in infancy and early childhood to child cortisol at age 48 months was examined in a prospective longitudinal sample of children and families (N = 1292)…


11.11.2013

Two Postdoc Employment Opportunities at Brown Medical School

Postdoctoral Fellowship in Maternal Smoking/Depression During Pregnancy and Infant Behavior Brown Medical School, Providence, RI Brown Medical School, Centers for Behavioral and Preventive Medicine is…


11.06.2013

New Spit Camp II - Analytical Strategy and Statistics for Salivary Bioscience

Spit Camp II at the Institute for Interdisciplinary Salivary Bioscience at the Arizona State University is an advanced workshop also led by Douglas Granger, PhD and focuses on analytical strategy and statistics…


10.02.2013

Breaking News: Novel Biomarker in Spit Linked to Stress, Resilience

A signaling protein typically linked to the survival, development or function of neurons may be an important player in understanding the body’s response to stress.


10.02.2013

Green space and stress: Evidence from cortisol measures in deprived urban communities

Author: Roe JJ, et al. (2013) Int J Environ Res Public Health A study in Scotland, UK, examined the relationship between green space in deprived urban neighborhoods and levels of perceived and physiological stress. Researchers collected saliva samples from residents…


09.30.2013

Salimetrics Cortisol Assay Superior in Comparison Study

The Salimetrics assay for cortisol is superior to all other commercially available products, according to a recent study published in the journal Psychoneuroendocrinology. This study, which compared results…


09.24.2013

Salivary interleukin-6 after psychosocial stress and its biological correlates in young adults

Author: Izawa, S, et al. (2013) Biological Psychology This study focused on salivary IL-6 and reports its temporal variation and biological correlates following acute psychosocial stress. Collection of saliva samples, measurement of heart rate, and assessment…


09.09.2013

Employment Opportunity: Arizona State University

The Institute for Interdisciplinary Salivary Bioscience Research (IISBR) at Arizona State University invites applications for Assistant Research Professor. This position is a non-tenure eligible annual…


09.05.2013

Salimetrics Launches a Better Salivary IL-6 ELISA/EIA Kit

With the Salimetrics salivary interleukin-6 (IL-6) assay kit, researchers now have an accurate way to measure IL-6 in saliva, aiding studies that examine topics such as oral inflammatory diseases, stress…


09.04.2013

Concurrent and Longitudinal Associations between Diurnal Cortisol and BMI across Adolescence

Author: Ruttle, P.L., et al. (2013) J Adolesc Health Childhood and adolescent obesity are at epidemic levels, with little known about the psychobiological underpinnings of obesity in youth. The current study examines concurrent (i.e., measured at the same…


08.23.2013

Arizona State University IISBR and Dr. Granger Announce Spit Camp: Open Enrollment

Dr. Granger and Arizona State University’s Institute for Interdisciplinary Salivary Bioscience Research (IISBR) announce open registration for 6 upcoming Spit Camps this year. The new facilities…


08.19.2013

Relationships between social behaviors, personality and cortisol in companion dogs

Author: Carrier, L.O., et al. (2013) Applied Animal Behaviour Sci The relationships between behavior, owner-rated personality, and cortisol were examined in companion dogs that visited a local off-leash dog park. In Study 1, salivary cortisol increased significantly…


08.12.2013

Diurnal patterns of salivary alpha-amylase & cortisol secretion in female adolescent tennis players

Author: Filaire, E., et al. (2013) Psychoneuroendocrinology This study examined the effects of training on diurnal patterns of salivary alpha-amylase (sAA), cortisol, and the ratio of sAA over cortisol (AOC) in 12 national adolescent female tennis players as related…


08.08.2013

Inflammatory mediators in saliva associated with arterial stiffness and subclinical atherosclerosis

Author: Labat, C, et al. (2013) Journal of Hypertension The aim of the present study was to establish the association of different salivary biomarkers of inflammation with subclinical cardiovascular disease. Salivary levels of CRP, leukotriene B4 (LTB4), prostaglandin…


08.05.2013

Neighborhood disadvantage and adolescent stress reactivity

Author: Hackman, D.A., et al. (2012) Front Hum Neurosci Lower socioeconomic status (SES) is associated with higher levels of life stress, which in turn affect stress physiology, but it is not clear if SES is associated with cortisol reactivity to stress. This…


07.29.2013

Salivary alpha-amylase, major depressive disorder, and antidepressant use in Netherlands NESDA Study

Author: Veen G, et al. (2013) Psychiatry Research The relationship between antidepressants and depression with sAA levels was studied. Differences in evening sAA levels were examined between patient groups (i.e., 752 current major depressive disorder…


07.26.2013

Update on salivary cortisol for the diagnosis of Cushing’s syndrome: methodological considerations

Author: Raff, H. (2013) Endocrine Late-night salivary cortisol (LNSC) is now considered the best approach to screen patients suspected of having endogenous hypercortisolism (Cushing's syndrome). The routine immunoassay for salivary…


07.16.2013

The Roles of Noradrenergic and Glucocorticoid Activation in the Development of Intrusive Memories

Author: Bryant RA, et al. (2013) PLoS ONE This study investigated the role of arousal during consolidation in the development of intrusive memories. Samples of salivary alpha-amylase (sAA) and cortisol were collected from participants at baseline…


07.08.2013

What we remember from a stressful episode

Author: Wiemers US, et al. (2013) Psychoneuroendocrinology A stressful episode is thought to be consolidated better because of a stress-induced activation of the hypothalamus-pituitary-adrenal (HPA) axis, but human experimental studies addressing this hypothesis…


07.05.2013

Cortisol, Alpha Amylase, and Daily Stressors in Spouses with Mild Cognitive Impairment

Author: Savla J, et al. (2013) Psychology and Aging This study examines the effects of daily primary objective stressors (behavioral problems exhibited by persons with mild cognitive impairment) and subjective stressors (unpleasant marital interactions)…


07.02.2013

Salivary Analytes & the Diagnostic Capacity for Distinguishing Chronic Adult Periodontitis

Author: Ebersole JL, et al. (2013) Journal of Clinical Immunology In this study, seven biomarkers associated with inflammatory and tissue destructive processes of periodontal disease were investigated. In a prospective cohort study design, analyte expression levels were…


06.26.2013

Is salivary alpha-amylase an indicator of autonomic nervous system dysregulations in mental disorder

Author: Schumacher, S., et al. (2013) Psychoneuroendochrinology A growing interest emerged in using salivary alpha-amylase (sAA) as a non-invasive, surrogate marker for sympathetic activity. Numerous studies applying stress protocols have demonstrated that sAA is highly…


06.19.2013

Salimetrics Redesigns Infant Swab for Faster, Easier Collection

A larger diameter infant swab with increased strength that will allow for greater fluid capacity is now available from Salimetrics. Salimetrics is offering its redesigned infant swab to make it easier…


06.14.2013

A multisystem stress response: Cortisol, alpha-amylase, & subjective stress in relationship conflict

Author: Laurent, H.K., et al. (2013) Physiol Behav. This study investigated associations among young adults' hypothalamic–pituitary–adrenal axis activity, autonomic nervous system activity, and subjective stress in response to interpersonal…


06.11.2013

Salivary progesterone as a biochemical marker to predict early preterm birth…

Author: Priya B, et al. (2013) BJOG Researchers in this study examined salivary progesterone as a biochemical marker for the prediction of early preterm birth in asymptomatic women who are at risk for preterm birth. The mean value of salivary…


06.04.2013

Salimetrics Launches a Faster, More Accurate, Salivary Melatonin Assay

A new salivary melatonin immunoassay promises precise and accurate results in less time by utilizing an exclusive antibody engineered by Salimetrics. The Salimetrics propriety format allows melatonin assay…


06.03.2013

Friendship network position and salivary cortisol levels

Author: Kornienko, O., et al. (2013) Social Neuroscience The association between friendship network position and cortisol levels are examined. Saliva samples taken from first-year nursing students in a highly competitive Nursing program are assayed for cortisol.…


05.28.2013

Love is more than just a kiss: A neurobiological perspective on love and affection

Author: de Boer, A., et al. (2013) Neuroscience Love, attachment, and truth of human monogamy have become important research themes in neuroscience. Brain activity patterns associated with romantic love, shown with fMRI, overlapped with regions expressing…


04.18.2013

ASU lands renowned expert in psychoneuroendrocrinology, Dr. Douglas A. Granger

Douglas A. Granger, a widely known psychoneuroendrocrinology researcher at Johns Hopkins University, will join the faculty of Arizona State University this summer.Granger has been appointed Foundation…


04.17.2013

Biobehavioral Reactivity to Social Evaluative Stress in Women With Borderline Personality Disorder

Author: Scott, L.N., et al. (2013) Personal Disord This study examined cortisol, alpha-amylase, and subjective emotional reactivity to social evaluative stress among women with Borderline Personality Disorder (BPD).  BPD participants had higher baseline…


04.12.2013

Salivary Cotinine Concentrations and Prevalence of Periodontal Disease in Young Japanese Women

Author: Tanaka, K., et al. (2013) J Periodontol In this study, Japanese researchers investigated the relationship between objectively assessed tobacco smoke exposure and periodontal disease. Results confirmed that salivary cotinine concentrations were…


04.04.2013

Impact of the testing environment on cortisol secretion and memory performance in older adults

Author: Sindi, S., et al. (2013) Psychoneuroendo Researchers compared salivary cortisol levels and memory performance in young and older adults tested in environments manipulated to be stressful (unfavourable condition) or not stressful (favourable condition)…


03.22.2013

Cortisol, Testosterone, and the Dual Hormone Hypothesis as it Relates to Status Among Teammates

Author: Edwards, D.A., et al. (2013) Hormones and Behav Recent research suggests that testosterone and cortisol jointly regulate dominance motivation and, perhaps, the status relationships that are affected by it. For this article, the results of six different…


03.04.2013

Salivary

Author: Out, D., et al. (2012) Child Maltreat This is the first study on adults' physiological reactivity to infant cry sounds and the association with intended harsh parenting using salivary α-amylase (sAA) as a novel and noninvasive marker…


02.18.2013

The Science of Early Life Toxic Stress for Pediatric Practice and Advocacy

Author: Johnson, S.B., et al. (2013) Pediatrics In this report, Johns Hopkins University researchers provide an overview of the science of toxic stress. Here, they summarize the development of the neuroendocrine-immune network, how its function is altered…


01.31.2013

Child maltreatment and gender interactions as predictors of differential neuroendocrine profiles

Author: Doom J.R., et al. (2013) PsychoNeuroEndo This study examines whether gender interacts with the stress of maltreatment to produce differential neuroendocrine profiles in children. Results showed that significant interactions between gender and…


01.31.2013

Involuntary Tobacco Smoke Exposure in Boston Public Housing Residents with Salivary Cotininine

A recent study from the Massachusetts General Hospital found a detectable level of the nicotine metabolite, cotinine, in 88% of non-smoking children and adults, indicating that they had been involuntarily…


01.28.2013

Does dampened physiological reactivity protect youth in aggressive family environments?

Author: Saxbe D.E. (2012) Child Dev. A longitudinal study from the University of Southern California, Los Angeles including 54 youth (average age 15.2 years) found that those with higher cumulative family aggression exposure showed lower…


01.24.2013

New date announced for Spit Camp in Cambridge, Friday, March 22nd

The Salimetrics Spit Camp Saliva Training Day teaches you all the skills you need to run a Salivary ELISA Assay. You'll learn the technology behind the Assay, practical pipetting skills, the full assay…


01.22.2013

DHEA and DHEA-S: Anabolic, Neuroprotective, and Neuroexcitatory Properties in Military Men

Author: Taylor, Marcus K. (2013) Military Medicine Evidence links dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) to crucial military health issues, including operational stress, resilience, and traumatic brain injury. This study…


01.15.2013

Adrenocortical regulation, eating in the absence of hunger and BMI in young children

Author: Francis, L.A. et al. (2012). Appetite Researchers at Penn State and Johns Hopkins University examined links between stress reactivity, eating behavior and body mass index in 5- to 9-year-old children. Saliva was collected before and after…


01.08.2013

Scholarship Opportunity for SRCD Spit Camp Workshop in Seattle, WA

Here’s your chance to attend a session of our international saliva training program where you will participate in a lecture-based workshop with a hands-on demonstration of saliva collection methods…


01.04.2013

Prenatal versus postnatal sex steroid hormone effects on autistic traits in children

Author: Baron-Cohen, S. et al. (2012). Mol Autism This study compares prenatal and postnatal sex steroid hormone levels in relation to autistic traits in 18 to 24-month-old children. Fetal testosterone (fT) and fetal estradiol (fE) levels were measured…


12.17.2012

Leadership is associated with lower cortisol levels and stress

Author: Sherman, G. D. et al. PNAS (2012) This 2-part study focused on stress measures via salivary cortisol in unique samples of real leaders. Part 1 found that, compared with non-leaders, leaders had lower levels of the stress hormone cortisol…


12.10.2012

Prefrontal serotonin transporter availability is associated with the cortisol awakening response

Author: Frokjaer, VG et. al. (2012) Eur Neuropsychopharmacol. Investigators studied the relation between cortisol response to awakening (CAR) and SERT binding in brain regions which are considered relevant to modify the cortisol awakening response. Thirty-two healthy…


12.10.2012

Collaborations in Salivary Research: New Saliva Biomarker Lab at UNL

Collaborations in Research: New saliva biomarker lab to be incorporated in the University of Nebraska-Lincoln (UNL) Athletic Performance Lab. See Page 12 on the following report:http://research.unl.edu/athleticsandresearch/report.pdf“Nebraska…


12.05.2012

Employment Opportunities at Brown Medical School

PROJECT MANAGER, BROWN MEDICAL SCHOOL, PROVIDENCE, RIMATERNAL SMOKING/DEPRESSION AND OFFSPRING RISK PROCESSES  Brown Medical School, Centers for Behavioral and Preventive Medicine is seeking a project…


11.30.2012

Salivary alpha amylase shows improved memory function after brief exercise

Researchers examined more than 50 adults between the ages 50 to 85, half of whom had memory deficits and half of whom were mentally healthy. Two groups—one that exercised on a stationary bike for…


11.26.2012

Salivary cortisol and the role of daily activities in youths’ stress physiology

Author: McHale, S.M. et al. (2012). J Adolesc Health. Researchers at Penn State University examined links between diurnal patterns of the stress hormone cortisol and time spent by adolescents in nine common daily activities. During eight consecutive nightly…