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Salivary Progesterone

Technical Summary

Analyte Summary
Analyte: ​Progesterone
Aliases: 4-pregenene-3,20-dione
Serum-Saliva Correlation: 0.80
Optimum Collection Volume: 125 μL*
*Add 300 µl to the total volume of all tests for liquid handling
Assay Summary
Methodology: ELISA
Sensitivity: 5 pg/mL
Assay Range: 10 pg/mL - 2430 pg/mL
Assay Type: Quantitative

Collect Saliva Samples

PROGESTERONE SALIVA COLLECTION CONSIDERATIONS

Better results begin with better saliva collection. This collection protocol features general considerations to maximize salivary ​Progesterone analysis. Use this analyte specific collection protocol to plan your collection methodology and sampling schemes.

APPROVED SALIVARY PROGESTERONE COLLECTION METHODS

Test Saliva Samples

@ Salimetrics
Salimetrics SalivaLab - Easy & Accurate
Order Code (lab): 5170
Transport Requirements: Ship on Dry Ice

Add DNA Analysis to My Study

Considerations for adding Salivary DNA to analyte Studies:

You can combine salivary analytes with easy, accurate, and affordable genomic testing using Salimetrics SalivaLab and the same sample that you are already collecting – no specialized saliva collection devices or additional samples are required.

Don’t know what SNPs are right for you? The SalivaLab’s DNA team specializes in genetic testing services, we recommend you Request a DNA Consult (gratis) to learn more about common considerations such as # of samples, participant ethnicity, and IRB Approval.

All DNA Services

DNA Extraction and Normalization
Single Nucleotide Polymorphism (SNP) Genotyping
VNTR & STR Analysis

References & Salivary Progesterone Research

    1. Tuckey, R.C. (2005). Progesterone synthesis by the human placenta.  Placenta, 26(4), 273-81.
    2. Strott, C.A., Yoshimi, T., Lipsett, M.B. (1969).  Plasma progesterone and 17-hydroxyprogesterone in normal men and children with congential adrenal hyperplasia. J Clin Invest, 48(5), 930-39.
    3. Soules, M.R., Clifton, D.K., Steiner R.A., et al. (1988). The corpus luteum: Determinants of progesterone secretion in the normal menstrual cycle. Obstet Gynecol, 71(5), 659-66.
    4. Eppig, J.J. (2001). Oocyte control of ovarian follicular development and function in mammals.  Reproduction, 122(6), 829-38.
    5. Veldhuis, J.D., Christiansen, E.C., Evans, W.S., et al. (1988).  Physiological profiles of episodic progesterone release during the midluteal phase of the human menstrual cycle: Analysis of circadian and ultradian rhythms, discrete pulse properties, and correlations with simultaneous luteinizing hormone release.  J Clin Endocrinol Metab, 66(2), 414-21.
    6. Junkermann, H., Mangold, H., Vecsei, P., Runnebaum, B. (1982). Circadian rhythm of serum progesterone levels in human pregnancy and its relation to the rhythm of cortisol.  Acta Endocrinol, 101(1), 98-104.
    7. Shah, C., Modi, D., Sachdeva, G., et al. (2005).  Coexistence of intracellular and membrane-bound progesterone receptors in human testis.  J Clin Endocrinol Metab, 90(1), 474-83.
    8. Djebaili, M., Guo, Q., Pettus, E.H., et al. (2005).  The neurosteroids progesterone and allopregnanolone reduce cell death, gliosis, and functional deficits after traumatic brain injury in rats. J Neurotrauma, 22(1), 106-18.
    9. Stein, D.G. (2008). Progesterone exerts neuroprotective effects after brain injury.  Brain Res Rev, 57(2), 386-97.
    10. Wagner, C.K. (2006). The many faces of progesterone: A role in adult and developing male brain.  Front Neuroendocrinol, 27(3), 340-59.

    1. Brown, S.L., Fredrickson, B.L., Wirth, M.M., et al. (2009).  Social closeness increases salivary progesterone in humans.  Horm Behav, 56(1), 108-111.)
    2. Vining, R.F., McGinley, R.A. (1987). The measurement of hormones in saliva: Possibilities and pitfalls.  J Steroid Biochem, 27(1-3), 81-94.
    3. Ellison, P.T. (1993). Measurements of salivary progesterone. In: Saliva as a diagnostic fluid, Malamud, D., Tabak, L., eds. Ann N Y Acad Sci, 694, 161-176.