DNA: Cholinergic Receptor, Nicotinic Alpha 3 Gene - CHRNA3

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Genomic DNA, purified using silica based...learn more

Recommended Collection Method

SOS (preferred), SIS, SCS or 500 uL Passive Drool


2-5 ug genomic DNA (?)

Special Considerations

Methods Paper: Assessing genetic polymorphisms using DNA extracted from cells present in saliva samples.

Collection Protocol Download PDF


  1. CHRNA3 cholinergic receptor nicotinic alpha 3 on NCBI
  2. Thorgeirsson, TE. et al. (2008). A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature. 452(7187), 638-642.
  3. Pillai, S. et al. (2009). A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci. PLOS Genetics. 5(3), e1000421.
  4. Cui, K. et al. (2014). Four SNPs in the CHRNA3/5 alpha-neuronal nicotinic acetylcholine receptor subunit locus are associated with COPD risk based on meta-analyses. PLOS ONE. 9(7), e102324.
  5. Zhang, J. et al. (2011). Nicotinic acetylcholine receptor variants associated with susceptibility to chronic obstructive pulmonary disease: a meta-analysis. Respiratory Research. 12(1), 158.
  6. Yang, L. et al. (2012). Functional Polymorphisms of CHRNA3 Predict Risks of Chronic Obstructive Pulmonary Disease and Lung Cancer in Chinese. PLOS ONE. 7(10):e46071.

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