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Featured Genes

Overview

Methodology:

Genomic DNA, purified using silica based membrane columns is analyzed by TaqMan® SNP Genotyping Assays run on the 7900HT real time PCR system

Recommended Collection Method: SalivaBio Infant's Swab (SIS)
SalivaBio Passive Drool
SalivaBio Oral Swab (SOS)
SalivaBio Children's Swab (SCS)
Yield: 2-5 ug genomic DNA
Special Considerations:

Methods Paper: Assessing genetic polymorphisms using DNA extracted from cells present in saliva samples.

Collection Protocol: Download PDF

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Featured Genes

Gene Symbol Gene Name Featured SNP's Related Research Field Additional Research
OXTR Oxytocin Receptor - OXTR

rs53576, rs2254298, rs1042778

stress reactivity, social perception, reproduction, empathy SNPedia
COMT Catechol-O-methyltransferase - COMT

rs4680

cognitive flexibility, impulse control, dopamine SNPedia
DRD2 Dopamine Receptor - DRD2

rs1076560, rs4648317, rs1800497, rs1801028

locomotion, cognition, neuroendocrine secretion, addiction SNPedia
NR3C1 Glucocorticoid Receptor - NR3C1

rs41423247, rs6198

stress, depression, metabolism, cell differentiation SNPedia
CHRNA3 Cholinergic Receptor, Nicotinic Alpha 3 Gene - CHRNA3

rs1051730, rs6495309

nicotine addiction, COPD, lung cancer SNPedia
BDNF Brain-Derived Neurotrophic Factor - BDNF

rs6265, rs12291063, C270T, rs7103411, rs2030324

learning, memory, depression, bipolar disorder, schizophrenia SNPedia
MR Mineralocorticoid Receptor - MR, NR3C2

rs2070951, rs149902988, rs138068105, rs199942132

stress, emotion, cognition, cortisol, depression SNPedia
FTO Fat Mass and Obesity - FTO

rs1421085, rs1121980, rs9939609

BMI, hip circumference, body weight SNPedia
CLOCK Circadian Locomotor Output Cycles Kaput - CLOCK

rs1801260, rs11932595

circadian rhythm, sleep-wake cycles, ADHD, obesity SNPedia
OPRM1 Mu-Opioid Receptor - OPRM1

rs1799971

alcoholism, dependence, depression SNPedia