04.08.2014 - Pretreatment cortisol levels predict posttreatment outcomes among older adults /w depression in CBT

Author: Holland JM, et al. (2013) Psychiatry Research.

The current study includes 54 older adults with depression who provided salivary cortisol samples at baseline and completed measures of depression at pretreatment and posttreatment, following a 12-week course of CBT. Structural equation modeling results suggest that those with higher daily outputs of cortisol and flatter diurnal slopes were less likely to benefit from CBT-a finding which if replicated could have important implications for clinical practice and future research.

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