Early Head Start Services Improve Infants’ Cortisol Regulation and Recovery
Improving Infants’ Stress-Induced Cortisol Regulation through Attachment-Based Intervention: A Randomized Controlled Trial Author: Berlin LJ, et al. (2019), Psychoneuroendocrinology. ABSTRACT Attachment-based parenting interventions have shown positive effects on early cortisol regulation, a key biomarker. Evaluations to date have focused on diurnal cortisol production in high-risk infants. It is important to understand whether attachment-based intervention may […]
Salivary DHEA-Cortisol Ratio Associations with Parental Maltreatment and Juvenile Incarcerated Male Psychopathy
Dehydroepiandrosterone (DHEA) and its ratio to cortisol moderate associations between maltreatment and psychopathology in male juvenile offenders Author: Kimonis ER, et al. (2019), Psychoneuroendocrinology. ABSTRACT This study examined whether DHEA and its ratio to cortisol moderated risk for psychopathology among incarcerated youth exposed to childhood maltreatment. Resistance to stress-related psychopathology under adversity was also examined in […]
Cortisol as a Target Mediator for Therapeutic Horseback Riding Effects in Youth with Autism Spectrum Disorder
Replication Pilot Trial of Therapeutic Horseback Riding and Cortisol Collection With Children on the Autism Spectrum Author: Zhaoxing P, et al. (2019), Frontiers. ABSTRACT We aimed to determine whether results of our prior randomized control trial [RCT; NCT02301195, (1)] of Therapeutic Horseback Riding (THR) for children and adolescents with autism spectrum disorder (ASD) could be replicated […]
Salivary Cortisol and DHEA are Inversely Correlated with Early Postnatal Growth and Blood Pressure in Extremely Preterm Children
Adrenal function links to early postnatal growth and blood pressure at age 6 in children born extremely preterm Author: Watterberg KL, et al. (2018), Pediatric Research. BACKGROUND: Low birth weight in term-born individuals correlates with adverse cardiometabolic outcomes; excess glucocorticoid exposure has been linked to these relationships. We hypothesized that cortisol and adrenal androgens would correlate […]
Low Salivary Alpha-Amylase Awakening Response Associated with Reduced Professional Efficacy
Reduced professional efficacy is associated with a blunted salivary alpha-amylase awakening response. Author: Landolt K, et al. (2018), Physiol Behav. ABSTRACT: The job demands-resources model (JD-R) has shown an ability to predict worker engagement and exhaustion, yet to our knowledge, research has not been conducted that assesses the JD-R model with physiological indicators of chronic stress […]
Cortisol Reactivity as a Predictor of Weight Gain Among Prenatally Drug-Exposed Girls
Cortisol reactivity and weight gain among adolescents who vary in prenatal drug exposure. Author: Armstrong B, et al. (2018), Pediatr Obes. OBJECTIVE: Low inhibitory control is linked with weight gain among youth. Inhibitory problems are associated with disruption to the hypothalamic-pituitary-adrenal axis cortisol response. Increased cortisol predicts appetite and weight gain (though may be gender specific). This study hypothesized that cortisol reactivity explains […]
Effect of Service Dogs on the Salivary Cortisol Awakening Response in Veterans with PTSD
The Effect of a Service Dog on Salivary Cortisol Awakening Response in a Military Population with Posttraumatic Stress Disorder (PTSD) Author: Rodriguez KE, et al. (2018), Psychoneuroendocrinology ABSTRACT Recent studies suggest a therapeutic effect of psychiatric service dogs for military veterans with posttraumatic stress disorder (PTSD), but are limited by self-report biases. The current study […]
Salivary Cortisol Associated with Stress and Sleep Patterns in Military Men
Morning Cortisol Is Associated With Stress and Sleep in Elite Military Men: A Brief Report. Author: Hernández LM, et al. (2018), Mil Med INTRODUCTION: Accumulating evidence suggests that trends in salivary cortisol after awakening may be reliable biological predictors of morbidity and mortality. In a sample of elite military men, our lab recently established summary parameters of morning cortisol as well as […]
Research highlights multi-system perspective for motivation, adolescent depressive symptoms, and HPA axis activation
An exploratory analysis of the joint contribution of HPA axis activation and motivation to early adolescent depressive symptoms. Author: Rudolph KD, et al (2018), Developmental Psychobiology BACKGROUND: This study examines the interactive contribution of the hypothalamic-pituitary-adrenal (HPA) axis and approach-avoidance motivation systems to longitudinal changes in depressive symptoms across the adolescent transition. In the summer […]
Social Context of Psychosocial Processes During Adolescent Development and the Psychobiology of the Stress Response.
Peer Networks, Psychobiology of Stress Response, and Adolescent Development Author: Kornienko, O, et al (2018), PLoS BACKGROUND: A consistent focus of research has been on understanding how social relationships shape the activity of the biological stress response system. Progress has been made in characterizing these dynamics at the level of the individual, but significantly less […]
Influence of Adverse Childhood experiences on stress regulation in BPD
Attachment – Related Regulatory Processes Moderate the Impact of Adverse Childhood Experiences on Stress Reaction in Borderline Personality Disorder. Author: Ehrenthal JC, et al (2018), Journal of Personality Disorders BACKGROUND: In this study, the authors explored whether attachment insecurity moderates the effects of adverse childhood experiences on stress reactivity in the context of borderline personality […]
Measuring Salivary Cortisol: Preventing stress-related disorder in early life
Cognitive control moderates parenting stress effects on children’s diurnal cortisol Author: Raffington L, et al (2018), PLoS BACKGROUND: This study investigated associations between parenting stress in parents and self-reported stress in children with children’s diurnal cortisol secretion and whether these associations are moderated by known stress-regulating capacities, namely child cognitive control. Salivary cortisol concentrations were […]
Salivary cortisol provides additional diagnostic value during ACTH1-24 stimulation test
Characterization of the serum and salivary cortisol response to the intravenous 250 µg ACTH1-24 stimulation test Author: Nolan BJ, et al (2018), Endocrine PURPOSE: The ACTH1-24 stimulation test is commonly used to assess the hypothalamic-pituitary-adrenal (HPA) axis. Given variations in CBG concentration and binding affinity, serum total cortisol may misclassify some patients. Salivary cortisol correlates well […]
Salivary bioscience supports pre-clinical evaluation of new medical device
Preclinical evaluation of the effect of the combined use of the Ethicon Securestrap® Open Absorbable Strap Fixation Device and Ethicon Physiomesh™ Open Flexible Composite Mesh Device on surgeon stress during ventral hernia repair. Author: Sutton N, et al. (2017), Dove Press Aim: To evaluate whether performing ventral hernia repairs using the Ethicon Physiomesh™ Open Flexible […]
Salivary cortisol, prematurity and developmental implications
Prematurity and perinatal adversity effects hypothalamic – pituitary – adrenal axis reactivity to social evaluative threat in adulthood. Author: Sullivan MC, et al. (2017), Developmental Psychology This study examined the long- term effects of prematurity and perinatal adversity on individual differences in stress- related reactivity and regulation of the HPA axis. A prospective sample of […]